In week 34, the slowdown in the circulation of SARS-CoV-2 continued with a drop in the number of hospital and intensive care admissions, although disparities existed across the country. The situation was particularly critical in Martinique and Guadeloupe, and preoccupying in Guyana. At the national level, the screening rate remained very high. The incidence rate, while still at high levels, decreased in all age groups, except for 0-9 year-olds (stable) and 3-5 year-olds (slight progression). The number of contacts reported by cases remained low, indicating the incomplete identification of contact persons. As of 31 August, 72.3% of the French population had received at least one vaccine dose, and 66.0% were fully vaccinated. In view of the start of the new school year and the return to work after the summer holidays, the vaccination of all eligible people is crucial. Vaccination should be combined with a high level of adherence to other preventive measures, notably by respecting protective measures, limiting contacts at risk, and self-isolating in the case of symptoms, confirmed infection, or contact with a confirmed case. Combining different measures is necessary to consolidate the current epidemic dynamics and preserve the hospital system.