Important questions remain regarding differences in geographical and age-specific mortality patterns as the COVID-19 pandemic evolved in consecutive waves, and how COVID-19 mortality compares to seasonal influenza. In a pandemic situation, excess all-cause mortality provides a more complete and robust measure than cause-specific mortality. Data submitted by 26 countries participating in the European Mortality Monitoring (EuroMOMO) network between 2020 and 2023 was analysed to quantify excess all-cause mortality during the COVID-19 pandemic. Excess mortality from this period was compared to previous influenza seasons from 2014 to 2019. Pooled estimates of excess mortality showed four main waves during the COVID-19 pandemic period, most markedly in people aged 65 years and above, with timing and magnitude that varied between countries. Here we show that prior to implementation of control measures and COVID-19 vaccination, excess mortality greatly exceeded typical seasonal influenza mortality, but later during the pandemic was at levels comparable to influenza.
Auteur : Nørgaard Sarah K, Nielsen Jens, Schjørring Christel B, Kalnæs Albert S, Richter Lukas, Chalupka Alena, Braeye Toon, Mekogo Serge Nganda, Athanasiadou Maria, Lytras Theodore, Denissov Gleb, Luomala Oskari, Pontais Isabelle, Zacher Benedikt, An der Heiden Matthias, Mellou Kassiani, Panagoulias Ioannis, Paldy Anna, Malnasi Tibor, Kelly Eva, Rotem Naama, de'Donato Francesca K, Di Blasi Chiara, Mossong Joël, Vergison Anne, England Kathleen, Calleja Neville, van Asten Liselotte, van de Kassteele Jan, Madsen Christian, Silva Susana, Rodrigues Ana Paula, Kranjec Natalija, León-Gómez Inmaculada, Gomez-Barroso Diana, Galanis Ilias, Farah Ahmed, Weitkunat Rolf, Andrews Nick, Clare Tom, Bucholc Magda, Bradley Declan T, William Naoma, Hamilton Mark, Jorgensen Pernille, Pebody Richard G, Bundle Nick, Søborg Bolette, Krause Tyra G, Mølbak Kåre, Vestergaard Lasse S
Nature communications, 2026, vol. 17, p. 1356
