Key Points

Vaccination of Pregnant Women: Encouraging Progress, but Significant Disparities by Vaccine and Region

In 2025, 64% of women who gave birth in the region were vaccinated against pertussis. This vaccination coverage has risen sharply since 2023 (+37 percentage points). However, regional disparities are evident, with the Hautes-Alpes achieving a high vaccination coverage rate (73%) and the Alpes-de-Haute-Provence recording the lowest (45%).

During the 2025–2026 RSV immunization campaign, 40% of eligible pregnant women were vaccinated against RSV. This figure represents a significant increase compared to the 2024–2025 campaign (+13 percentage points). At the regional level, coverage ranges from 30% in the Alpes-de-Haute-Provence to 57% in the Hautes-Alpes. If the mother was not vaccinated against RSV during pregnancy, the infant can be protected from birth through an injection of monoclonal antibodies.

Vaccination of people aged 65 and older: low but rising flu vaccination coverage

For the first time since the COVID-19 pandemic, influenza vaccination coverage among people aged 65 and older has increased by nearly 3 percentage points, with 46% of people vaccinated during the 2025–2026 season. However, it still remains below the 75% target set by the World Health Organization (WHO).

In the Provence-Alpes-Côte d’Azur (PACA) region, among people aged 65 and older at high risk for pneumococcal infections, 22% were properly vaccinated against pneumococcal infections in 2025.
Only 3% of people aged 65 and older were vaccinated against shingles in 2025.

Vaccination of residents and staff working in long-term care facilities for the elderly: varying levels of protection between residents and staff

Residents in long-term care facilities: Flu vaccination coverage was high (81% during the 2025–2026 season) and exceeded the 75% threshold recommended by the WHO. In contrast, COVID-19 vaccination coverage remains insufficient, at 55%.

Staff working in long-term care facilities: Flu vaccination coverage remains insufficient, with only 24% vaccinated despite recommendations and a slight upward trend during the 2025–2026 season.

Vaccination Support

Overall vaccination acceptance is high but remains among the lowest in France: 79% of those aged 65 to 79 say they are in favor of vaccination in general.