Work-related mental health issues are currently a frequent topic of discussion, and incidents such as suicides in the workplace have brought them into sharp focus. The fact that both many companies and public authorities are addressing these issues underscores the societal importance of this topic. With the aim of monitoring these occupational risks, this article provides a brief overview of the epidemiological literature and the data available in France to address this issue. The epidemiological literature now includes a substantial body of methodologically rigorous studies, suggesting that links exist between psychosocial occupational exposures and impaired mental health. Furthermore, many authors agree on the causal nature of these links. Depressive disorders—ranging from symptoms to a full-blown depressive episode—are by far the most studied. In France, data are already available to enable an initial assessment of this phenomenon and to describe mental health issues among worker populations according to their occupational activities. These data can help identify certain occupational categories or sectors that are particularly vulnerable. This is a first step in a comprehensive public health approach. Primary or secondary prevention measures should be recommended and implemented by the relevant authorities, both at the institutional level and in the field. (R.A.)