Key Points

• A total of 222 cases of mpox have been reported to Santé publique France since January 1, 2024, including 7 since the last update on December 19 and diagnosed in 2024.

• The first case of clade Ib was confirmed by the National Reference Center for Orthopoxviruses in January 2025.

• All reported cases involve adults: 213 men and 9 women.