Key Points

• Significant decrease in pediatric HUS cases reported to Santé publique France in 2024:

  • 87 cases reported in 2024 versus 143 in 2023

  • Annual incidence of 0.79 cases per 100,000 children under 15, the lowest incidence observed in nearly 20 years

• Children under 3 years of age remain more affected than other age groups, but with a declining incidence in 2024:

  • Incidence of 1.78 cases per 100,000 children in 2024 versus 4.01 cases per 100,000 children in 2023

  • Stable proportion of children under 3 years of age among reported cases (60% of cases in 2024)

• Low number of suspected clusters and no documented outbreaks in 2024