This fact sheet, drawn from the 6th report of the National Suicide Observatory (ONS), traces trends in suicidal behavior since 2010 and the main associated sociodemographic factors. A descriptive analysis of the reported motives behind suicidal behavior, as well as of treatment and suicidal intent, complements these initial findings. The data are drawn from the Santé publique France Health Barometer. Citation: Léon C. Prevalence and trends in suicidal behavior in metropolitan France in 2021 - Results from the Health Barometer. In: National Suicide Observatory. Suicide: Growing Distress Among Young Women and End-of-Life Issues - Understanding Suicidal Behavior Through the Lenses of Age and Gender - 6th Report. Paris: DREES, February 2025, pp. 163–171. The 6th ONS report is available for download on the DREES website (https://www.drees.solidarites-sante.gouv.fr).