Key Points

• Between 2021 and 2023, apart from the standardized incidence and prevalence rates for ischemic heart disease—which were higher in the Paca region than at the national level—all other cardio-neuro-vascular indicators examined in this bulletin were comparable to or even lower than national indicators.

• The standardized incidence rate of patients hospitalized for ischemic heart disease in the PACA region (554 per 100,000 inhabitants) was higher than that of France (459), with an average of 24,438 patients hospitalized per year in the region. The standardized prevalence was 5.9% in the region in 2022, slightly higher than that of France (5.5%). The standardized mortality rate (2020–2022), however, was slightly lower in the region (53 per 100,000 inhabitants) compared to the national rate (59).

• Between 2021 and 2023, the standardized incidence rate of patients hospitalized for heart failure in the PACA region was lower than that of France (292 vs. 344 per 100,000 inhabitants), with an average of 13,442 patients hospitalized per year in the region. In 2022, the standardized prevalence was 2.4% in the region, comparable to that of France (2.5%). The standardized mortality rate (2020–2022) was also comparable in the region compared to France (46 per 100,000 inhabitants in PACA and in France).

• Between 2021 and 2023, the standardized incidence rate of patients hospitalized for stroke in the PACA region was slightly lower than that of France (217 vs. 231 per 100,000 inhabitants, respectively), with an average of 9,733 patients hospitalized per year in the region. The standardized prevalence was 1.9% in the region in 2022, comparable to the national prevalence (2.0%). The standardized mortality rate in the region (55 per 100,000 inhabitants) was comparable to that of France (58).

• At the subregional level, several departments in the region had higher incidence rates (notably Bouches-du-Rhône, Alpes-de-Haute-Provence, and Vaucluse), with some heterogeneity at the subdepartmental level.