Santé publique France was commissioned by the Pays de la Loire Regional Health Agency to assess the relevance and feasibility of conducting an epidemiological study in the Saint-Nazaire area (Loire-Atlantique) to determine the impact of industrial pollution on the health of the local population. This summary document presents the request, its context, the key points of the response, the outlook, and other actions by Santé publique France regarding the monitoring of population health around industrial areas on a national scale.