Key Points

• An average incidence rate of typhoid fever in Mayotte of 17 cases per 100,000 inhabitants between 2016 and 2024, which is nearly 70 times the incidence rate in mainland France (0.25 cases per 100,000 inhabitants)

• Cases reported year-round, but a surge at the end of the rainy season from late February to June

• A hospitalization rate of 81% across all age groups and 90% among children aged 0 to 5

• The municipalities of Koungou and Mamoudzou are the most affected and report the highest number of typhoid cases

• As of April 2, 2025, 70 cases of typhoid had been reported, a level well above those reported in the previous five years during the same period

• In 2025, 49% of cases for which an investigation could be conducted reported consuming water from a river or a well