Introduction - In 2008, the prevalence of hypertension was estimated at 44% among people aged 30 to 69 living in Mayotte, with two out of three people with hypertension unaware of their diagnosis. The objective of this study was to provide a new estimate of the prevalence of HTN in Mayotte in 2019, assess awareness of the diagnosis and management, and describe the characteristics of the hypertensive population. Methods - The data were derived from the Unono Wa Maore cross-sectional survey, conducted in Mayotte. The analyses focused on the adult population aged 18 to 69 who completed the questionnaire and underwent a health examination including at least two blood pressure measurements (n=2,620). Hypertension was defined by a self-reported history of hypertension or by systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg at the clinical examination. Results - In 2019, the prevalence of hypertension was estimated at 38.4% (95% CI: [36.1–40.7]) in the population of Mayotte aged 18 to 69 years. The prevalence was similar among men (38.5%) and women (38.3%, p=0.95). The prevalence of certain risk factors was high, with 75% of those with hypertension being overweight or obese (vs. 53% of those without hypertension), 13% reported having diabetes (vs. 4%), and 69% were economically inactive (vs. 63%). Among those with hypertension, 48% were aware of their diagnosis. Women were more likely to be aware of their diagnosis than men (56% of women with hypertension vs. 38% of men with hypertension, p