Key Points

• Continuous circulation of SARS-CoV-2 between March 2020 and February 2023, resulting in waves of varying magnitude.

• No distinct seasonal pattern, with resurgences linked to various factors (emergence of a variant, return to school, large gatherings, etc.).

• A sharp increase in surveillance indicators in late 2021 linked to the emergence of the Omicron variant, followed by the circulation of sublineages of this variant with similar characteristics (increased transmissibility, immune evasion, but lower severity).

• Trends in epidemiological indicators similar to those observed at the national level, but with a lower impact on hospital admissions compared to other regions.

• Regional vaccination coverage exceeds the national coverage rate for the primary vaccination series completed with at least one booster dose.