As part of its mission to conduct epidemiological surveillance of occupational risks, Santé publique France has established, in partnership with the Medical Labor Inspection (IMT) of the Ministry of Labor, an epidemiological surveillance system for musculoskeletal disorders (MSDs). In Hauts-de-France, the program is jointly conducted by Santé publique France, the IMT of the Regional Directorate for the Economy, Employment, Labor, and Solidarity (Dreets), and the Regional Health and Social Observatory (OR2S). It relies on the voluntary participation of occupational physicians and collaborating physicians in the region, who report twice a year with the support of nurses. This brochure presents the results of the two-week reporting periods conducted during 2023 in the region.