As part of its mission to conduct epidemiological surveillance of occupational risks, Santé publique France is implementing, in collaboration with the Medical Labor Inspection (IMT) of the Ministry of Labor and the regional observatories of participating regions, a system for the epidemiological surveillance of work-related diseases (MCP). The program relies on the voluntary participation of occupational physicians and collaborating physicians in the region, who, with the support of nurses, report all occupational diseases encountered during their consultations with workers over two consecutive weeks known as “MCP Fortnights.” This brochure presents the results of the MCP Fortnights conducted during 2023 in the Grand Est region.