Key Points

• In Week 06 (February 8–14, 2021), epidemiological surveillance indicators showed that SARS-CoV-2 continued to circulate at high levels in the Île-de-France region.

• Across the departments of Île-de-France, disparities in epidemiological indicators were again observed amid uncertainty regarding the spread of variants.

• Pressure on the hospital system remained high and persistent in the region.

• Given the rapid and increasing spread of more transmissible variants, a worsening of the epidemiological situation in the coming weeks remains possible.

• Single-dose vaccination coverage in Île-de-France increased to 2.7% of the general population.