The government sought to establish, at the national level, a set of indicators designed to track changes in the health of the population in France. Since its creation in 1998, the Department of Occupational Health (DST) of the French Institute for Public Health Surveillance (InVS) has focused on developing surveillance programs to regularly produce such data and thereby contribute to improving understanding of occupational risks. Data sources have expanded over time, and in 2009 the DST established a program for the regular production of indicators designed to provide a national-level overview of health issues related to the work environment, as well as their trends over time. These indicators are derived from various sources and will be published regularly on the InVS website: www.invs.sante.fr. This third issue focuses on musculoskeletal disorders (MSDs) of the upper extremities. In this document, readers will find data on the frequency of these conditions in terms of prevalence and incidence, as well as on the frequency of exposure to the main known risk factors, broken down by sex, age, occupational categories, and major economic sectors. Readers will also find information on the proportion of upper-limb MSDs attributable to work, by occupational category and major economic sector, as well as on the extent of underreporting in the tables of compensable occupational diseases. Finally, a number of questions help put the presented results into perspective.