The monitoring of antibiotic use conducted as part of the ATB-Raisin network contributes to the appropriate use of antibiotics. The objectives are to enable each healthcare facility to describe and analyze its antibiotic use in comparison with a comparable group and to cross-reference this data with bacterial resistance data. Systemic ATBs in class J01 of the Anatomical Therapeutic Chemical (ATC) classification, rifampicin, and oral imidazoles, dispensed during inpatient stays, were expressed in terms of defined daily doses (DDD) and reported according to national and World Health Organization recommendations (ATC-DDD system, 2011). Resistance data were collected for seven bacteria/antibiotic pairs. The 1,262 participating healthcare facilities in 2011 accounted for nearly 60% of inpatient days and had consumed 372 DDDs per 1,000 inpatient days (ID). The most commonly used antibiotics were the amoxicillin-clavulanic acid combination (31%), amoxicillin (17%), and ofloxacin (5%). Median antibiotic consumption ranged from 52 DDD/1,000 HD in psychiatric hospitals to 653 in military training hospitals. Variations were observed across specialties, ranging from 58 DDD/1,000 HD in psychiatry to 1,580 in intensive care. In the 614 healthcare facilities that have participated every year since 2008, consumption in 2011 remained stable compared to 2010, whereas it had increased by 6% between 2008 and 2010. Resistance data were consistent with those from specific networks. Network-based monitoring of detailed consumption data allows each healthcare facility to assess its position relative to others, exchange information on practices and organizational structures, and track evolving trends. Analysis of antibiotic consumption should be supplemented by an evaluation of clinical practices. (R.A.)