In France, in 2018, the estimated number of new cases of promyelocytic acute myeloid leukemia was 228, including 146 in men and 82 in women. Key points: Standardized net survival of 74% at 1 year and 67% at 5 years for individuals diagnosed between 2010 and 2015; Difference in net survival by age at diagnosis as early as 1 year of follow-up: ranging from 97% at age 20 to 58% at age 80; Net survival at 5 years exceeds 92% among individuals diagnosed before age 50; Early excess mortality is more pronounced among individuals aged 70 and 80 at diagnosis; Net survival stabilizes after 1 year among individuals diagnosed before age 60 and after 3 years for older age groups.