La Santé de l'homme dedicates this issue to French Guiana and Réunion. For French Guiana, the topics covered include: access to drinking water, dengue prevention, training for professionals in the care of migrants, and community health workers in isolated villages along the Maroni River. For Réunion: the fight against addiction, primarily alcohol; the prevention of teenage pregnancy and abortions among minors; the “Health-City Workshops” to reduce health inequalities; and the mobilization of the public and professionals against mosquitoes. With an article on Mayotte, the future 5th overseas department.