The authors report a collective intoxication with "mad honey" on Reunion Island, which occurred in 2008. Most patients presented with showed faintless, bradycardia, hypotension and dizziness, consistent with ingested food containing grayanotoxins. All patients fully recovered with a symptomatic treatment. A survey around the hives where the honey was collected, showed the presence of large quantities of Agauria salicifolia (Ericaceae family), an endemic plant in the south-western Indian Ocean and rich in grayanotoxins. A close relationship between these two events was strongly suspected. A monitoring system for the manufacture of honey should be implemented. (R.A.)