The patient is a 61-year-old woman who had been visiting Senegal regularly since 2001 without residing there. At the time, she was working in Dakar (in the paramedical field). She arrived in Dakar in early October 2004 and spent the All Saints’ Day weekend in Saly Portudal. Upon her return to Dakar (Day 0), she developed a high fever. The patient was referred to a private clinic (“Hospital 1”) in Dakar for suspected malaria. On Day 0+3, she developed a hemorrhagic syndrome with bruising, bleeding gums, petechiae, and then hematemesis before being transferred on Day 0+6 to the intensive care unit at a second hospital (“Hospital 2”) in Dakar. As her clinical condition worsened, she was repatriated from Dakar to Rennes on Day 0+9 via a medical evacuation flight chartered by a German company. The patient was transferred by private ambulance from the airport to the Pontchaillou University Hospital (CHU), where she was admitted on Day 10 and placed in isolation in the intensive care unit. As her clinical and laboratory findings improved, she was transferred to the infectious diseases ward two days later. A specimen collected on Day 10 and sent to the National Reference Center (CNR) for Hemorrhagic Fevers (Dr. H. Zeller, Lyon) tested positive for IgM antibodies specific to Crimean-Congo Hemorrhagic Fever (CCHF) and negative for IgG, with viral genome detection by RT-PCR. The results were reported on Day 10. As the patient had recovered and the maximum duration of viremia had passed, she returned to her home in Rennes the following day. The CNR reported the CCHF diagnosis the same day to the Directorate General of Health (DGS) and the French Institute for Public Health Surveillance (InVS). The Pasteur Institute in Dakar reported the same day the positive result of the analysis of samples taken on Day 6 at Hospital 2. In total, this case of imported FHV was hospitalized for 9 days in a French university hospital without any special measures being taken (other than the patient’s hospitalization in a single room and adherence to standard precautions). This paper presents the investigation conducted to detect any secondary cases.