As part of PRSE 2, the Haute-Normandie Regional Health Agency sought to involve Cire Normandie in order to assess the feasibility of measuring polychlorinated biphenyl (PCB) exposure among the population of the Haute-Normandie coast. Cire reviewed the available literature on the subject and consulted experts from the French Agency for Food, Environmental and Occupational Health & Safety (ANSES), the Seine-Normandy Water Agency (AESN), the Seine-Aval Public Interest Group (GIP), and the French Institute for Public Health Surveillance, Department of Health and Environment (InVS-DSE). Currently, due to PCB contamination in fish, fishing is regulated on a number of waterways in the region. Thus, it appears that the environmental situation related to PCB contamination in fish is monitored and regulated to prevent exposure of the local population. If a study were to investigate PCB exposure among people on the Normandy coast, it should focus primarily on populations that consume seafood. However, it appears that there is no information on the size of this population, nor on the actual extent of exposure, and it is established that fishermen in Seine-Maritime continue to fish and consume the fish despite their knowledge of the bans. Furthermore, regarding the individual and collective benefits that a study on PCB exposure in the population would provide, it appears that no such study is currently underway, and the scientific findings on the health effects of PCBs on humans remain incomplete. From a collective perspective, the benefit would be linked to an overall improvement in the level of exposure and the health status of the affected population. The study would provide maximum consumption frequencies for fish that are strong bioaccumulators of PCBs without long-term risk to humans. However, these recommendations already exist. All the data collected by the Cire show that, given the available knowledge and with regard to developing recommendations for the individual and collective benefits of the population in the local context of the Upper Normandy coast, it appears unproductive to conduct a contamination study. Indeed, such a study would result in proposing recommendations and restrictions that are already in place, without providing any additional benefits for public health. (R.A.)