Objective: Our objective was to describe dietary intake and certain nutritional biomarkers among adults in Guadeloupe and Martinique in 2013–2014, based on data collected in the “Kannari: Health, Nutrition, and Chlordecone Exposure in the French West Indies” survey. Methods: After a random selection of individuals aged 16 and older based on a three-stage sampling design (islands, households, individuals), the selected participants answered a questionnaire about their health status in person at home, followed by two telephone follow-up calls within 24 hours on non-consecutive days. Biological samples were collected from adults aged 18 and older. The descriptive analysis accounts for the sampling design and is weighted using adjustments based on the INSEE population census and variables predictive of participation in each component of the survey. Results: Among eligible adults, 651 in Guadeloupe and 662 in Martinique responded to two 24-hour recalls. One-quarter of them consumed at least 400 g of fruits and vegetables per day (recommendation of the National Nutrition and Health Program (PNNS)). Furthermore, 9 out of 10 adults consumed dairy products in quantities below the PNNS recommendations, and one-quarter exceeded the consumption benchmark for the "meat, fish, eggs" group. Few differences were observed between the departments. Intake of "meat, fish, and eggs," starchy foods, added fats, and sugary drinks was higher among men than among women. Total energy intake and intake of alcohol and calcium were generally low, but the macronutrient balance was in line with recommendations. Iron-deficiency anemia affected 6.7% of premenopausal women in both departments. In addition, 30.9% of men and 14.9% of women were at risk of folate deficiency. Conclusion: The situation observed here shows changes in dietary patterns compared to those recorded in the Escal survey in Martinique ten years earlier. Efforts to raise awareness and improve access to health-promoting foods therefore remain necessary.