Issues related to mental health and work are often addressed using data generated by statistical and epidemiological analyses. However, the connections established by these disciplines do not provide a complete understanding of the underlying phenomena. Clinical analysis can be useful here. The specific program for monitoring mental health in relation to occupational activity, entitled Samotrace, invites us to engage in this unique dialogue between epidemiologists and clinicians. To discuss these issues, we propose illustrating them with a clinical vignette describing a prevention initiative in a cell phone store. Through this example, we demonstrate that clinical data gathered from employees’ accounts of their experiences can help individuals suffering from work-related issues and facilitate effective prevention initiatives. This example also sheds light on the gap between spontaneous, abstract, conventional interpretations and clinical listening that is attentive to work and its challenges. In this regard, it gives us hope for a cross-fertilization between epidemiology and clinical practice. It is to this bold and unprecedented challenge that the Samotrace program invites us. (R.A.)