Esteban measures numerous indicators—many of which have yet to be thoroughly studied—to establish a more comprehensive approach to health at the national level.

The health examination takes place at a Health Examination Center (CES) of the Health Insurance Fund or at home, depending on the participant’s choice.

It includes:

• anthropometric measurements: height, weight, waist and hip circumferences

• three blood pressure readings

• a respiratory function test (assessment of lung capacity via spirometry)

• an interview to gather information about your primary care physician (including contact information), your general health, your history of respiratory diseases, etc.

• samples (blood, hair, and urine) used to measure biological and nutritional parameters (complete blood count (CBC), serum creatinine, fasting blood glucose, lipid profile, glycated hemoglobin, ferritin and transferrin, folates…), as well as the measurement of environmental biomarkers (metals, cotinine, pesticides, perfluorinated and polybrominated compounds, dioxins and PCBs, phthalates, bisphenol A, etc.).

Biological analyses

A portion of the biological samples is stored to create a biobank (collection of biological samples) to enable long-term studies.

The biological analyses are supplemented by a questionnaire regarding your environment (household products, UV exposure, personal care products, pesticides), your diet, and your medical history.

The test results are communicated to you personally and, upon your request, forwarded to your primary care physician.

Some analyses are conducted only on a subset of participants (sub-sample) and cannot be automatically shared with you personally. However, these results are available upon express written request.

Medical Care

If you agree, this examination will be supplemented by a collection of information on treatments, hospitalizations, care, and medications you have received over the past three years.

Physical activity

Your physical activity is assessed using a simple questionnaire, completed at home with the help of an interviewer.

Diet

The dietary survey is conducted (for adults aged 18 to 74) either by phone with a dietitian (a call lasting about 15 minutes) or online, where you enter the information yourself. This survey is used to describe the foods you consume (type, composition, and quantity) over three different days within a three-week period.