Introduction: Cannabis is the most commonly used illicit psychoactive substance in France. In 2005, the MILDT launched cannabis clinics (CC), which, over the first 12 months, served 15,200 users and 12,400 people in the users’ social circles. Method: As soon as this program was established, the OFDT conducted a questionnaire survey among professionals seeing patients in a given month to describe the profiles and behaviors of users. Patients were then followed for 14 weeks. Results: Approximately 95% of CCs participated, representing 4,202 clients, including 3,000 users, the majority of whom were males (80%) and minors or young adults (90%). Half reported daily cannabis use. Nearly 40% of referrals were court-ordered (primarily among young adult males), compared to 30% of unsolicited requests (mostly from females) and 30% of referrals at the request of a third party (for minors). Nearly 60% of users are diagnosed with substance abuse or dependence: at the same time, 47% of all clients are seen by a doctor or psychologist. Discussion-Conclusion: CCs function as a platform for identifying, informing, and/or referring individuals experiencing substance abuse or dependence. This initial assessment provides new insights, particularly regarding “dropout” during follow-up, which will be explored in greater depth in the 2007 edition of the survey. (R.A.)