Over the past few decades, the incidence of testicular cancer has continued to rise. In France, the estimated incidence rate increased by an average of 2.5% per year between 1980 and 2005. The objective of this study was to describe national trends and regional disparities in the rate of patients undergoing surgery for testicular cancer. The data were drawn from the national PMSI database for 1998–2008. Hospital stays for testicular cancer among patients residing in metropolitan France were identified using ICD-10 codes and surgical procedure codes. A total of 21,179 hospital stays corresponding to patients who underwent surgery for testicular cancer were selected. The average age at diagnosis was 37 years. The rate of patients undergoing surgery, standardized to the global population in 2008, was 6.7 per 100,000. An average annual increase of 2.5% in the rate was observed. Regional disparities in the rates of patients undergoing surgery were also observed (2004–2008). The highest rates were found in Alsace, Lorraine, Brittany, and the Pays de la Loire, and the lowest rates in Languedoc-Roussillon and Île-de-France. The observed increase in the rate of patients undergoing surgery for testicular cancer is consistent with trend analyses of national incidence. The rate of patients undergoing surgery in 2004–2008 varied by a factor of 1 to 1.25 across regions. The reasons for these variations are unclear. PMSI data are useful for the epidemiological surveillance of this cancer, particularly for studies of geographic variations. (R.A.)