Of the population residing in France, 637,000 people died there in 2023. The age-standardized death rate is 828 deaths per 100,000 inhabitants, which is 59 deaths per 100,000 inhabitants fewer than in 2022 and 11 fewer than in 2019, just before the first year of the health crisis. This decline in 2023 is largely driven by the drop in Covid-19-related deaths. In contrast, deaths from respiratory and infectious diseases are slightly higher. The two leading causes of death remain, for both women and men, tumors and cardio-neurovascular diseases. Clear regional disparities are observed: mortality is higher in the overseas departments and regions (DROM) and, in metropolitan France, in the North and East; and it is significantly lower in Île-de-France. Mortality from tumors varies less across the country than that from cardiovascular and cerebrovascular diseases. In the DROMs (except Mayotte), it is lower than the national average. Mortality from cardiovascular and cerebrovascular diseases is higher there. Significant regional disparities are also observed for infectious, endocrine, and respiratory diseases, as well as for COVID-19. Areas outside the influence of cities have higher mortality rates than the centers of major metropolitan areas, particularly for cardiovascular and cerebrovascular diseases and external causes. Mortality rates due to endocrine diseases, diseases of the nervous system, the digestive system, and mental disorders are also higher in these areas; this is also the case in urban centers with fewer than 700,000 inhabitants.