Key Points

• Following the reorganization of the national organized cancer screening program in January 2024, the targeting, frequency, and procedures for sending invitations to individuals were modified. Some data—particularly regarding invitations—are still missing, but the number of invitations sent in 2024–2025 appears to be slightly lower than in 2022–2023. 
• The standardized participation rate of the target population in the PNDOCS was 47.4% in 2025 and 43.9% in 2024, for an average of 45.6% for the 2024–2025 period. By comparison, it was 46.6% for the 2022–2023 period. 
• This decline in PNDOCS participation is observed across all age groups, with the exception of a recent stabilization among those aged 50–54. 
• When comparing 2024–2025 to 2022–2023 across mainland France, a decline is observed except in Normandy, Hauts-de-France, Nouvelle-Aquitaine, Auvergne-Rhône-Alpes, Occitanie, and Corsica. 
• When comparing 2024–2025 to 2022–2023 in the overseas departments and regions (DROM), excluding Mayotte, participation has stagnated in Martinique and French Guiana, risen slightly in Guadeloupe, and fallen sharply in Réunion. 
• Participation in the PNDOCS continues to trend downward. The trend in participation rates shows that this steady decline began in the mid-2010s.