The tuberculosis notification rate has declined in Île-de-France since 2000 and then stabilized from 2011 to 2014. More recently, in 2016, an increase in cases was reported in Paris. The objective of this article is to present recent trends in tuberculosis in Île-de-France and in each of the region’s departments over the three-year period from 2015 to 2017. This report covers cases of active tuberculosis reported in Île-de-France between 2015 and 2017, with 2015 used as the reference year. The incidence rates of reported tuberculosis cases were calculated based on INSEE data for the corresponding year. The rates by department were age-standardized, using the Île-de-France population as the reference population. The tuberculosis notification rate in Île-de-France increased significantly between 2015 and 2017, rising from 14.6 per 105 inhabitants in 2015 to 15.8 per 105 inhabitants in 2017 (+8.2%, p<0.01), suggesting a possible reversal of the trend. All departments in the Île-de-France region exceeded the threshold of 10 tuberculosis cases per 105 inhabitants in 2017. Subregional disparities were observed, notably with a more significant increase in the number of cases in the capital, reaching a rate of 16.8 per 105 inhabitants in 2017 (compared to 13.5 per 105 in 2015, p<0.01). The reporting rate among people born abroad increased, in contrast to that observed among people born in France, which decreased. Among the tuberculosis cases reported in Île-de-France, an increase is observed among men, among residents in group living facilities, and, among people born abroad, among recent arrivals. An upward trend in active tuberculosis cases has been observed in Île-de-France since 2016. The populations affected by this increase are those most vulnerable to precarious living conditions and overcrowding, particularly foreign-born individuals, those living in group housing or who are homeless, and recent arrivals in France. These findings underscore the need to continue and strengthen the adaptation of screening programs for these at-risk populations.