An elevated risk of death by suicide has been observed among farmers in several French and international studies. In this context, Santé publique France (formerly the Institut de veille sanitaire) and the Caisse centrale de la mutualité sociale agricole (CCMSA) have joined forces to produce regular indicators of suicide mortality among the farming population. The study population includes all farm managers and their assisting spouses who were professionally active in 2010 and 2011. This report also presents trends in suicide mortality within this population between 2007 and 2011. The study population comprises an average of 481,657 people, 69% of whom are men and 31% women. Over the two-year period, there were 253 suicide deaths among men and 43 suicide deaths among women. A comparison of suicide mortality among active farmers with that of men of the same age in the general French population shows a 20% excess of suicides in 2010, particularly pronounced in the 45–54 age group and in the dairy cattle sector. For the year 2011, only farmers aged 45 to 54 showed a significantly higher excess suicide mortality rate than that of the general population of similar age. The excess suicide mortality observed in 2010 follows two years in which an excess suicide mortality rate was also observed among farmers. The cattle farming sector appears to be particularly affected by suicide. These results confirm the need for continued surveillance in this population.