Severe cases of hemolytic uremic syndrome (HUS) in children: new cases reported; health authorities issue guidelines

Press Contacts

Directorate-General for Competition, Consumer Affairs, and Fraud Prevention
communication@dgccrf.finances.gouv.fr

Directorate General for Health
presse-dgs@sante.gouv.fr

Public Health France
presse@santepubliquefrance.fr

Since January 1, 2022, authorities have been investigating serious cases of hemolytic uremic syndrome (HUS) reported across the country. Epidemiological, microbiological, and traceability analyses have confirmed a link between several cases and the consumption of frozen pizzas from the Buitoni brand’s Fraîch’Up line contaminated with Shiga toxin-producing Escherichia coli bacteria.

Given this situation, authorities are asking anyone who has Buitoni-brand Fraîch’Up pizzas not to eat them and to dispose of them. Every household is urged to check their freezers to ensure they do not contain any.

It is also recommended that anyone with frozen pizzas in their freezer that have been removed from their packaging—and whose brand or product line cannot be formally identified or is unclear—should not consume them and should dispose of them.

As a precautionary measure, on March 18, the company initiated a recall of all pizzas in the Buitoni Fraîch’Up line, which have been on the market since June 2021. Authorities are fully mobilized to ensure the effectiveness of the recall measures implemented, notably through more than 10,000 inspections across various distribution channels. In addition to these inspections, if consumers notice that Buitoni-brand Fraîch’Up pizzas are still being sold, they are encouraged to report them via the SignalConso platform.

As of March 28, 2022, 75 cases are under investigation, including 41 cases of HUS with similar characteristics, representing 14 more cases compared to the last update on March 17. An additional 34 cases are currently under investigation.

These 75 cases have occurred in 12 regions of mainland France: Hauts-de-France (16 cases), Nouvelle-Aquitaine (11 cases), Pays de la Loire (10 cases), Île-de-France (9 cases), Brittany (7 cases), Grand Est (5 cases), Auvergne-Rhône-Alpes (4 cases), Centre-Val de Loire (4 cases), Provence-Alpes-Côte d’Azur (3 cases), Bourgogne-Franche-Comté (2 cases), Normandy (2 cases), and Occitanie (2 cases).

The affected children are aged 1 to 18, with a median age of 7. Two children have died.

Authorities remind the public that after consuming the products subject to the recall, it is important to seek medical attention promptly and report this consumption if:

  • within 10 days, individuals experience diarrhea, abdominal pain, or vomiting;

  • within 15 days, individuals experience signs of extreme fatigue, paleness, or a decrease in urine output, with urine becoming darker in color.

If no symptoms develop within 15 days of consumption, there is no cause for concern.

Pediatric hemolytic-uremic syndrome

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Hemolytic uremic syndrome is a primarily renal complication of infections caused by Shiga toxin-producing Escherichia coli. Although rare, it is a serious condition that primarily affects young...

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