Key points

In mainland France

In mainland France, 2019 saw an increase in the incidence of invasive infections caused by Haemophilus influenzae, Streptococcus pneumoniae, Streptococcus pyogenes, and, to a lesser extent, Streptococcus agalactiae, compared to 2018.

Incidence trends, 2009–2019

• Haemophilus influenzae - The incidence of invasive infections caused by Haemophilus influenzae shows an upward trend, rising from 1.1 cases per 100,000 in 2009 to 1.9 cases per 100,000 in 2019 (p<10^⁻⁴).

• Streptococcus pneumoniae - The incidence of invasive Streptococcus pneumoniae infections decreased from 14.6 in 2009 to 8.3 cases per 100,000 in 2014 (p<10^⁻⁴) and then increased to 10.5 per 100,000 in 2019 (p<10^⁻⁴).

• Streptococcus pyogenes - The incidence of invasive Streptococcus pyogenes infections remained stable until 2015, ranging between 2.5 and 3 cases per 100,000 (p=0.088), then increased to 4.1 cases per 100,000 in 2019 (p<10^⁻⁴).

• Streptococcus agalactiae - The incidence of invasive Streptococcus agalactiae infections remained stable at 4.0 from 2009 to 2015 (p=0.602) and then increased to 5.1 cases per 100,000 in 2019 (p<0^.00⁴).

• Listeria monocytogenes - The incidence of invasive Listeria monocytogenes infections shows a slight upward trend from 0.6 in 2009 to 0.7 in 2019 (p=0.050).

• Neisseria meningitidis - The incidence of invasive Neisseria meningitidis infections shows a downward trend from 1.2 in 2009 to 0.8 cases per 100,000 in 2019 (p<10^⁻⁴).

In Overseas Territories

In the overseas departments and regions (DrOM), the adjusted case counts and incidence rates of meningitis and isolated bacteremia caused by Haemophilus influenzae, Streptococcus pneumoniae, Streptococcus pyogenes (group A), Streptococcus agalactiae (group B) in the DrOM in 2019 are presented in Tables 10a through 10e. In 2019, Mayotte had the highest incidence of invasive infections.

In metropolitan and overseas France

In 2019, the incidence of invasive infections was higher in the overseas departments and regions (DrOM) than in metropolitan France, except for Streptococcus pneumoniae (9.5 vs. 10.5 cases per 100,000 (p=0.007); 7.3 vs. 4.1 cases per 100,000 (p<10⁻^⁴) for Streptococcus pyogenes and 10.1 vs. 5.1 cases per 100,000 (p<10⁻⁴) for Streptococcus agalactiae. The incidence of invasive Haemophilus influenzae infections is comparable in the overseas departments and territories and in mainland France (1.7 vs. 1.9 cases per 100,000 (p=0.341)).

Learn more

• Pneumococcal infections: 2019 annual data

• 2019 data on listeriosis from mandatory reporting

• 2019 data on Neisseria meningitidis meningitis from mandatory reporting