Introduction: Since 2002, hepatitis E surveillance has been coordinated by the National Reference Center (CNR) for Enteric Hepatitis Viruses (hepatitis A and E). In recent years, significant scientific advances have improved our understanding of hepatitis E virus (HEV) infection in industrialized countries. The objective is to describe the data sources and epidemiological findings regarding HEV infection during the 2002–2016 period in metropolitan France. Methods: Data were obtained from the CNR (number of people tested, imported/autochthonous cases [IgM/PCR-positive], genotypes), two private central laboratories (number of requests for diagnostic tests, number of positive cases [IgM/PCR]), the National Health Data System’s inter-regime consumption database (number of tests reimbursed in outpatient care), the Information Systems Medicalization Program database (number of hospital stays/patients hospitalized for hepatitis E), and cluster case investigations. Results: Between 2002 and 2016, the number of individuals for whom samples were submitted for hepatitis E diagnosis increased exponentially (209 vs. 76,000). An increase in the number of diagnosed cases was also observed, primarily involving locally acquired cases (9 vs. 2,292). Since 2007, more than 90% of locally acquired strains have been genotype 3. Concurrently, the number of people hospitalized for hepatitis E has increased (57 vs. 653), with higher annual incidence rates in southern regions. The suspected sources of contamination during clusters of cases were most often the consumption of raw pork liver sausages. Conclusion: starting in 2010, the availability of diagnostic tests and improved knowledge of hepatitis E led to a considerable increase in the number of people tested, resulting in a rising incidence of locally acquired cases. Pigs, the main reservoir of HEV in France, are the source of foodborne transmission, particularly in products made from raw liver. Prevention relies on informing consumers about the need to cook these products thoroughly.