Glycol ethers constitute a group of oxygenated solvents comprising more than eighty compounds, about thirty of which are commonly available on the global market. These solvents have been used for many years due to their physicochemical properties. Being both hydrophilic and lipophilic, glycol ethers are used in a very wide range of products for industrial and domestic use, including so-called "water-based" products: paints, inks, varnishes, adhesives, household cleaning products, cosmetics, cutting fluids, and plant protection products... to such an extent that a large portion of the general population is exposed to these compounds. Glycol ethers are suspected of causing toxic effects on reproduction and development in humans (decreased male fertility, increased risk of spontaneous abortions, fetal malformations), as well as hematotoxicity. In France and abroad, data on glycol ether exposure levels in the general population are lacking. The available studies concern adults with or without occupational exposure in specific regions (Brittany, Nord-Pas-de-Calais). The Esteban cross-sectional study (Health Study on the Environment, Biomonitoring, Physical Activity, and Nutrition) made it possible for the first time to measure glycol ether exposure levels in the French mainland population based on a subsample of 500 adults and 200 children, enrolled between April 2014 and March 2016. The results showed that the entire population (adults and children) was exposed to at least one of the eight metabolites tested (MAA, MEAA, EAA, EEAA, BAA, PAA, PhAA, and 2-MPA). The investigation into the determinants of glycol ether exposure levels revealed associations with the use of everyday consumer products, such as cosmetics and household products in particular. PhAA and MAA were the two most frequently detected metabolites and those with the highest average concentrations. Some concentrations exceeded health threshold values established abroad for the adult population. It would therefore be necessary to reduce exposure and continue monitoring glycol ether concentrations in the French population to track changes in population exposure to these compounds over time.