Under the auspices of the Network for the Alert, Investigation, and Surveillance of Nosocomial Infections (Raisin) and in collaboration with the Study Group on Healthcare Workers’ Risk of Exposure to Infectious Agents (Geres), methods for monitoring blood-exposure incidents (BEIs) have been the subject of a consensus and a national network since 2002. All BSE incidents reported to the occupational physician between January 1 and December 31, 2009, are documented on a voluntary, anonymous, and standardized basis. In 2009, 16,472 BSE incidents were documented, 60% of which were reported by paramedical staff, and 80% were percutaneous injuries, primarily needle sticks. Compliance with glove use is improving (70% in 2009), but proximity to the sharps container remains stable at around 70%, results confirmed within the stable cohort between 2006 and 2009. In 2009, standard precautions were not followed in 45.2% of percutaneous AES (N=5,940), resulting in a still high number of preventable accidents. The serological status of the source patient remains unknown in one out of five cases. However, the trend emerging from the stable cohort points toward improved documentation of the source patient’s serological status. Antiretroviral prophylaxis was prescribed to 4.8% of healthcare professionals, a slight increase compared to 2008. The network’s national coverage in 2009 (26.2% of healthcare facilities and 51.6% of hospital beds) has been increasing since 2002. The incidence is 7.3 AES per 100 hospital beds. Based on the 434,809 hospital beds recorded in France (SAE 2008 data), we estimate that 31,741 AES were reported in 2009 to occupational physicians at French healthcare facilities. When comparing this result with the 2004 data from the same network (an incidence of 8.9% and an estimated 41,429 AES), this represents a decrease of approximately 9,688 AES. Although the estimate is empirical, this suggests that significant progress has been made in terms of patient safety. Continuing and strengthening this momentum is the objective of the 2009–2013 National Program for the Prevention of Nosocomial Infections. (R.A.)