Objective: Cardiovascular diseases are the second leading cause of death in France. Certain occupational risk factors have been implicated. The objective of this study is to analyze premature cardiovascular mortality according to two socio-occupational indicators: social class (SC) and economic sector (ES). Method: The socio-occupational data were derived from the DADS panel analysis. Vital status was obtained from INSEE, and causes of death from the CépiDC. Age-standardized mortality rates were calculated based on SO and the last known OS for coronary and cerebrovascular diseases. The results cover the period 1976–2002 among men born in France aged 35 to 64. Results: Analysis by SC indicates an increasing gradient from the managerial category to the manual labor category for coronary mortality (ratio of 1 to 1.9) and cerebrovascular mortality (1 to 2.5). Analysis by economic sector reveals disparities: the three sectors with the highest rates of coronary heart disease are mining and quarrying, accommodation and food services, and real estate and business services. For cerebrovascular mortality, the sectors with the highest rates are accommodation and food services, construction, and real estate. Conclusion: Our study highlights, on the one hand, a social gradient in mortality, and on the other hand, occupational sectors with high mortality rates that share several socio-occupational risk factors (harmful noise, shift work, atypical schedules). Despite its limitations, this study suggests that socio-occupational factors are associated with cardiovascular mortality and that a better understanding of these factors is necessary to implement prevention programs. (R.A.)