Serology plays an important role in the diagnosis of trichinellosis because the clinical signs (fever and muscle pain) of this disease are nonspecific. Many techniques have been studied, but very few are commercially available, and comparative analyses of their performance have been conducted only very rarely. Here, we compared the performance of four commercially available kits: two ELISA kits, one Western blot kit, and one latex agglutination test. The sensitivity and specificity of the different tests were evaluated using 60 sera from patients with trichinellosis and 70 control sera. All four kits had a sensitivity of 100% for confirmed cases of trichinellosis; specificity was 98.6% for the Western blot kit, 93% for the latex agglutination test, and 87% and 77% for the two ELISA kits, respectively. Cross-reactions were observed primarily in patients with other helminth infections.