Objectives: The objective of this study was to provide estimates of the prevalence of overweight and obesity in France. The frequency of the metabolically healthy obesity (MHO) phenotype was also calculated. Methods: The study population consisted of 28,895 participants from the Constance cohort, aged 30 to 69 years in 2013. Weight, height, waist circumference, and blood pressure were measured. Blood tests were performed. Abdominal obesity was defined as a waist circumference ≥94 cm for men and ≥80 cm for women, and sociodemographic data were collected via questionnaires. Results: The prevalence of overweight was 41.0% and 25.3%, respectively, among men and women. The prevalence of overall obesity was 15.8% for men and 15.6% for women; the prevalence of abdominal obesity was 41.6% and 48.5%, respectively, among men and women. The prevalence of the MHO phenotype, excluding treatment, was lower among men (25.7%) than among women (51.8%). Conclusion: Overweight affects nearly half of the population in France. These data confirm the significance of this nutritional condition in terms of public health.