Introduction: Each year in France, burns result in several hundred deaths and significant physical and psychological sequelae. Methods: Data from the Medical Information Systems Program (PMSI) for the period 2008–2011 were analyzed for metropolitan France. All short-stay hospitalizations with a primary diagnosis of burn, coded as T20 to T32 in the International Classification of Diseases, 10th Revision (ICD-10), were included. Results: In 2011, in mainland France, 8,670 people (residing in mainland France) were hospitalized for burns, corresponding to 11,651 hospital stays. Children aged 0 to 4 years accounted for more than a quarter of the victims, and males accounted for 63%. For 11.5% of patients hospitalized in burn treatment centers, the burn was severe. The crude incidence rate of hospitalized burn victims was 13.7 per 100,000 inhabitants. It was particularly high among children under 5 years of age (60.7) and among men (17.9 vs. 9.9 among women). The number of in-hospital deaths was 215, representing an in-hospital case-fatality rate of 2.5%. Conclusion: These epidemiological findings, consistent with the international literature, characterize burn patients and their hospital care. They highlight the importance of developing prevention strategies, particularly for children once they begin walking, and for the elderly, among whom burns are less frequent but more severe. They could be very useful for planning and organizing hospital resources.