For the past decade, the monitoring of antibiotic resistance in Campylobacter has been organized by the Directorate General for Food within the French poultry, swine, and cattle sectors, and its implementation has been entrusted to the laboratories of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES). Based on samples collected in slaughterhouses according to a sampling plan representative of the production sectors, strains of Campylobacter jejuni and C. coli are isolated and identified, and the minimum inhibitory concentrations of the antibiotics of interest are determined. For poultry, resistance to macrolides remains very low for C. jejuni and generally below 20% for C. coli, but resistance to fluoroquinolones has increased steadily, reaching 51% for C. jejuni and nearly 70% for C. coli in 2010. In the swine sector, in 2009, 34% and 45% of C. coli strains were resistant to ciprofloxacin and erythromycin, respectively. In cattle, resistance to fluoroquinolones has risen sharply, increasing from 29.7% to 70.4% between 2002 and 2006. Resistance to gentamicin is rare in all three sectors. Data from this surveillance program contribute to the annual European report on antibiotic resistance in zoonotic and indicator bacteria. (R.A.)