Key Points

• 132 cases of IIM in the Grand Est region from 2017 to 2022;

• Cases reported in all departments except Meuse;

• A decline in the incidence rate in 2020 and 2021 but an increase in 2022;

• An incidence rate in 2022 similar to those observed in 2018 and 2019;

• People aged 15–24 were most affected in 2022;

• 10% of cases died during the 2017–2022 period;

• A majority of serogroup B cases during the 2017–2022 period;

• Emergence of an IIM B strain in Strasbourg in November 2022.