Only Plasmodium falciparum requires preventive measures; the other species do not pose a life-threatening risk and respond well to chloroquine: Travelers should take steps to avoid insect bites. Antimalarial drugs include: quinine, used for treating severe attacks (injectable form); chloroquine, which remains the standard prophylaxis in chemoresistant areas; and amodiaquine, which should no longer be used for prophylaxis. Among the antifolates, proguanil is well tolerated and rarely leads to resistance. It is available only at the central pharmacy of Paris hospitals; Fansidar is not recommended for prophylaxis due to the risk of Stevens-Johnson syndrome; mefloquine is effective. Only chloroquine and proguanil are safe for pregnant women and young children. Prophylaxis is standard for short stays (less than one month). It must be continued for 4 weeks after return. For repeated or prolonged stays, prophylaxis must be tailored to the individual.