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WHO Issues Alert on Measles Resurgence in Europe: Is France Affected?

Following the WHO’s warning about the resurgence of measles cases in 2023, particularly in Europe, Santé publique France provides an update on the spread of the virus and reiterates the importance of vaccination.

Measles

thematic dossier

The World Health Organization (WHO) warns that the number of measles cases surged in 2023 across Europe compared to the previous year (42,000 cases in 2023), primarily in Russia and Kazakhstan. The ECDC, for its part, reports just over 2,000 cases to date in EU/EEA countries. France, which has infant vaccination coverage close to the target needed to eliminate the disease, has recorded just over 100 cases in 2023 (unconsolidated data).

Only high vaccination coverage can eliminate measles in Europe

The measles virus is among the most contagious, and there is no specific treatment for the disease. Only very high and sustained vaccination coverage could allow the disease to disappear permanently. In France, measles vaccination is mandatory for all children born on or after January 1, 2018. The first dose is administered at 12 months and the second between 16 and 18 months. People born since 1980 should have received a total of two doses of the vaccine, regardless of their history with any of the three diseases (measles, mumps, and rubella).

An improvement in vaccination coverage (VC) with the measles-mumps-rubella (MMR) vaccine has been observed since the implementation of mandatory vaccination for infants, and the goal of 95% two-dose vaccination coverage by age 2 could soon be achieved. Recent VCO data at 24 months show 94.3% for the first dose and 91.3% for the second. However, there remain populations with insufficient vaccination coverage, particularly among adolescents and young adults, as well as within specific populations who are isolated from the healthcare system. Vaccination coverage against the three diseases, as reported by 18- to 35-year-olds, is estimated at 90.4% in metropolitan France, with significant regional disparities (Public Health France Barometer 2021). Therefore, to interrupt the circulation of the virus and achieve the WHO’s goal of eliminating measles, verifying measles vaccination status and updating vaccinations remain essential in older age groups.

How is the measles virus currently circulating in Europe?

During the COVID-19 pandemic, the epidemiology of measles in France was marked by a near absence of viral circulation, with a total of 41 cases reported between April 2020 and December 2022. In 2023, the measles virus began circulating again in Europe. The ECDC report dated January 11, 2024, noted more than 2,242 cases reported by 22 countries between January and November 2023, with nearly two-thirds of the cases reported by Romania. Given the suboptimal vaccination coverage for the second dose (≤95%) in most EU/EEA countries, more measles cases can be expected in the coming months and in the spring. The most recent data for Europe from the ECDC show a notification rate for the EU/EEA region over the past 12 months of 4.98 per million inhabitants. The rate for France is 1.64 (with 111 cases), and five countries have higher rates than France (Austria (19.16); Belgium (6.54); Estonia (3.00); Liechtenstein (76.32); Romania (88.70)).

Epidemiological surveillance based on reporting and mandatory reporting

Measles surveillance relies on mandatory reporting and a network of partners. It enables measures to be taken in response to a case (such as post-exposure vaccination) and allows health authorities to provide an appropriate response when clusters of cases are detected (such as catch-up vaccination for individuals who are unvaccinated or incompletely vaccinated, in accordance with current national recommendations). As a reminder, all cases of measles (clinical, confirmed, or laboratory-diagnosed) must be reported immediately by clinicians and laboratory professionals to the Regional Health Agency (ARS) under whose jurisdiction they fall. The National Reference Center (CNR) for measles, rubella, and mumps viruses performs viral genotyping and assists in the investigation of clusters and transmission chains.

A detailed epidemiological report on measles cases in France in 2023 will be published during the first quarter of 2024.

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