Reducing the incidence of surgical site infections (SSIs) is one of the objectives of the national program to combat nosocomial infections (NI). Since 1999, interregional surveillance of SSIs has been coordinated by the Network for Alert, Investigation, and Surveillance of Nosocomial Infections (Raisin). Each year, participating surgical departments collect data from a list of "priority" specialties regarding the patient and the procedure, including components of the NNIS risk index. All included patients must be followed up through the 30th postoperative day (90 days for orthopedic surgery and spinal procedures). SISIs are defined according to standard criteria. In 2015, the number of departments participating in the surveillance of priority procedures remained unchanged from 2014: 909 surgical departments for 106,737 procedures. The breakdown by specialty and their respective ISO rates were: 276 orthopedic surgery departments (ISO rate = 1.15%), 254 gastrointestinal surgery departments (1.74%), 229 obstetrics and gynecology departments (1.63%), 77 trauma departments (0.73%), 79 lower extremity vein removal surgery departments (0.38%), 89 urology departments (2.76%), 43 neurosurgery departments (1.07%), 42 bariatric surgery departments (1.47%), 10 coronary surgery departments (4.18%), 10 thoracic surgery departments (0.74%), and 5 plastic and reconstructive surgery departments (3.47%). As noted in previous years, not only has the slowdown in the decline in incidence been confirmed, but in 2015 there was also an increase in ISO rates for breast surgery, abdominal wall hernias, osteosynthesis, abdominal hysterectomies, and transurethral resections of the prostate. The influence of BMI on the incidence rate of SSI was demonstrated in gastrointestinal surgery and obstetrics and gynecology, of diabetes in gastrointestinal surgery, and of hypertension in bariatric surgery. A prescription for antibiotic prophylaxis (AP) recommended by the SFAR and administered was a protective factor against SSI incidence in orthopedics, obstetrics and gynecology, and neurology (compared to recommended but unadministered prescriptions). Finally, a preoperative shower was a protective factor against the incidence of surgical site infections in gastroenterology and obstetrics-gynecology, and shaving was significantly associated with a higher rate of surgical site infections in obstetrics-gynecology (compared to hair removal by clipping, scissors, or chemical methods).