Atypical mycobacterial (AM) infections generally occur in immunocompromised patients, but they are also observed in immunocompetent patients following invasive procedures, particularly cosmetic procedures. Since 2001, 20 reports (57 cases) of ATI, seven of which (43 cases) were linked to cosmetic procedures, have been received by the Coordination Centers for the Control of Nosocomial Infections (CClin), the Departmental Directorates of Health and Social Affairs (Ddass), and the Institute for Public Health Surveillance. Non-surgical procedures performed in private clinics were implicated in four reports (40 cases): mesotherapy, carboxytherapy, and sclerotherapy for microvaricosities. The other three reports (three cases) involved surgical procedures—facelifts and breast implant placement. Practice evaluations conducted by the CClin and Ddass for five reports revealed non-compliance with standard precautions and inappropriate use of tap water for cleaning injection devices or disinfecting the skin. Microbiological investigations (National Reference Center) identified and compared strains from patients and the environment: in one report (16 cases following mesotherapy), the M. chelonae strain isolated from tap water was similar to those isolated in 11 cases. Healthcare-associated MA infections are rare but can be severe. These cases highlight the importance of reporting infections associated with healthcare and invasive procedures in private practice. (R.A.)