Introduction - The "Spirale" and "Espri" programs aim to identify retired employees (Spirale) and retired tradespeople (Espri) who were exposed to carcinogens during their working lives, so that they can receive medical follow-up care. A cohort follow-up study is also being conducted. Populations and methods - A mail-in questionnaire is sent to retirees to identify occupational exposure to asbestos and, for Spirale, to wood dust. Exposure assessment is conducted by occupational health experts (Espri) or by the Health Examination Centers (CES) of the Health Insurance system (Spirale). Only retirees who were exposed at “moderate” or “high” levels are referred for medical follow-up. Results - During the pilot phases, nearly 70% of participants in Spirale were considered potentially exposed to asbestos and invited to a CES; more than 40% attended the CES, and 48% of them were found to require medical follow-up. For Espri, this level of exposure affected 83.5% of men and 5.6% of women. Discussion and conclusion - The initial results of the Spirale and Espri intervention programs are largely positive, and their expansion to the entire country is desirable. The cohort follow-up study that has been established will make it possible to assess their impact on social recognition (recognition as an occupational disease or compensation through FIVA) and health benefits.