Use of DNA arrays for the analysis of outbreak-related strains of Listeria monocytogenes

Publié le 1 December 2006
Mis à jour le 10 septembre 2019

We evaluated the discriminative power and usefulness of the DNA array technology as compared to DNA macrorestriction pattern analysis for monitoring epidemiologically related clusters of Listeria monocytogenes strains that differ slightly in DNA macrorestriction patterns. We show that this approach allows clarifying the genetic basis of the pattern variations. In the reported outbreak, the differences were due to phage excision, showing the power of this technique in epidemiological studies.

Auteur : Doumith M, Jacquet C, Goulet V, Oggioni C, van Loock F, Buchrieser C, Martin P
International journal of medical microbiology, 2006, vol. 296, n°. 8, p. 559-62