Cases of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection were recently detected for the first time in Ireland. CA-MRSA infections have been reported in recent years from many countries around the world. In a study comparing 117 CA-MRSA isolates from three continents, it was shown that in all cases, methicillin resistance was encoded by the SCCmec IV genetic complex. In addition, all the isolates contained the Panton-Valentine leukocidin (PVL) genes lukS-PV and lukF-PV. These encode the synergistic PVL proteins LukS and LukF, which damage host cell membranes. (Introduction)
Auteur : Rossney A, Morgan P, O'Connell B
Eurosurveillance. European communicable disease quarterly, 2005, vol. 10, n°. 4-6, p. 132-3
